Frozen Tissue H&E Staining – Elevated by RTFaSt™
Precision. Speed. Diagnostic Clarity.
Intraoperative frozen section analysis demands the highest levels of accuracy—when every second counts and diagnostic precision is critical. That’s why MedInvent’s Rapid Stain Mohs H&E Kits, powered by RTFaSt™ tissue processing, deliver a breakthrough solution for frozen tissue staining, optimized for both standard H&E and immunohistochemistry (IHC).
Figure 1. RTFaSt1 fixation, HE x60 objective
Figure 2. 95% Ethanol fixation, HE x60 objective
Figure 3. RTFaSt1 fixation, HE x60 objective
Figure 4. 95% fixation, HE x60 objective
Figure 5. RTFaSt1 fixation, HE x20 objective
Figure 6. 95% fixation, HE x20 objective
Why Upgrade to Rapid Stain H&E?
Traditional frozen section H&E protocols haven’t changed in over 50 years. While functional, they often rely on alcohol fixatives that can compromise staining quality—especially in melanocyte-rich tissues such as early-stage melanoma.
The Rapid Stain Mohs H&E Kits, using the proprietary RTFaSt1 Fixative, redefine frozen section preparation by:
• Preserving cellular morphology without shrinkage
• Providing vivid contrast — bluer nuclei and pinker connective tissue
• Enhancing visibility of actinocytes, inflammatory cells, and melanocytes
• Offering superior results for MART1 IHC staining (melanocyte marker)
See the difference: Compared to alcohol-based methods, RTFaSt1-fixed slides show improved cellular detail and richer staining quality—even at high magnification.
Optimized for Immunohistochemistry
Frozen tissue sections fixed with RTFaSt1 show exceptional performance in IHC, particularly for MART1, a key melanocyte marker in Mohs surgery for melanoma. Results show:
Backed by RTFaSt™ Innovation
The RTFaSt™ reagent system, developed by MedInvent’s team of expert pathologists, dramatically reduces tissue processing times — from 19 hours to as little as less than 1 hour — without compromising stain performance across H&E, IHC, and special stains.
Benefits:
• Compatible with existing equipment
• Increases same-day diagnosis rates
• Improves patient care and lab efficiency
• Saves on operational costs
RTFaSt™ reagents are being tested across cytology, Mohs, surgical, and veterinary applications, with data showing enhanced clarity and time savings across tissue types.
Partner With Us
Whether you manage a high-throughput dermatopathology lab or a focused Mohs practice, MedInvent’s Frozen Tissue H&E solutions offer the edge in both performance and efficiency.
Contact us today to request a demo or learn more about how RTFaSt™ can transform your lab.